Liposomal vitamin C, which is enfolded within a lipid bilayer, produced a greater blood plasma concentration of vitamin C than plain unencapsulated vitamin C in humans. Intravenous vitamin C was far superior to oral vitamin C however.
Plasma vitamin C in milligrams per deciliter of plasma
Following administration of 4 grams (4000 mg) vitamin C
| 1 hour | 3 hours | |
|---|---|---|
| Oral vitamin C | 1.6 | 2.2 |
| Oral liposomal vitamin C | 2.2 | 3.4 |
| Intravenous vitamin C | 27.0 | 10.0 |
Source: Nutrition & Metabolic Insights June 2016